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10.1038/s41433-020-0820-5 210

No NAD+ is a dinucleotide coenzyme

The SLC25 family of proteins are mitochondrial carriers essential for the functioning of eukaryotes because they transport nutrients such as amino acids, carboxylic acids, fatty acids, cofactors, inorganic ions, and nucleotides across the mitochondria inner membrane for energy conversion and maintenance of the cell 34

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The threshold where ROS generation surpasses cellular antioxidant capacity culminates in cellular architecture erosion, underscoring the incipient demise (Qin Y