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Despite conflicting observations, we have presented in this review, we believe we have highlighted substantial evidence to consider drug-induced mitochondrial toxicity as a risk factor for developing insulin resistance

Although GHK-Cu has attracted significant attention due to its potential skin repair and anti-aging properties, the current commercial landscape does not provide sufficient financial incentives for a company to pursue an FDA New Drug Application (NDA)

Despite the encouraging advances in therapeutic development, further research is urgently needed to establish more personalized and accessible treatment paradigms for MASLD in the near future [95]