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Abbreviations ABTS: 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) AG490: JAK2 Inhibitor AKT: Protein Kinase B AML: Acute Myeloid Leukemia AMPK: AMP-activated protein kinase AP-1: Activator Protein 1 AR: Androgen Receptor ATP: Adenosine Triphosphate Bax: Bcl-2-associated X protein Bcl2: B-cell lymphoma 2 BIR: Baculoviral IAP Repeat CDK: Cyclin-Dependent Kinase CHOP: C/EBP Homologous Protein CML: Chronic Myeloid Leukemia CYP: Cytochrome P450 DPPH: 1,1-diphenyl-2-picrylhydrazyl DNA: Deoxyribonucleic Acid EMT: Epithelial-Mesenchymal Transition EPR: Enhanced Permeability and Retention ER: Endoplasmic Reticulum Fas: Fas Cell Surface Death Receptor GC: Gas Chromatography HCT-116: Human Colon Cancer Cell Line HER-2: Human Epidermal Growth Factor Receptor 2 HIF-1: Hypoxia Inducible Factor 1 HOS: Human Osteosarcoma Cell Line HPLC: High-Performance Liquid Chromatography HSC3: Human Squamous Cell Carcinoma Cell Line Hsp70: Heat Shock Protein 70 Hsp90: Heat Shock Protein 90 IL-1: Interleukin 1 beta JAK: Janus Kinase JNK: c-Jun N-terminal Kinase LPS: Lipopolysaccharide MAPK: Mitogen-Activated Protein Kinase MCF-7: Human Breast Cancer Cell Line MDA-MB-231: Human Breast Cancer Cell Line MDM-2: Mouse Double Minute 2 homolog MMP: Matrix Metalloproteinase MS: Mass Spectrometry NAD + : Nicotinamide Adenine Dinucleotide NCOR2: Nuclear Receptor Corepressor 2 NF-B: Nuclear Factor kappa-light-chain-enhancer of activated B cells NMR: Nuclear Magnetic Resonance NQO1: NAD(P)H Quinone Accepting Oxidoreductase 1 PARP: Poly(ADP-ribose) Polymerase PC-3: Prostate Cancer Cell Line PEG: Polyethylene Glycol PI3K: Phosphoinositide 3-Kinase Pin1: Peptidyl-prolyl cis/trans isomerase PLC: Phospholipase C PTX: Paclitaxel RAW264.7: Murine macrophage cell line ROS: Reactive Oxygen Species S6K: Ribosomal Protein S6 Kinase STAT3: Signal Transducer and Activator of Transcription 3 TLC: Thin-Layer Chromatography TNF-: Tumor Necrosis Factor alpha UAE: Ultrasound-Assisted Extraction VEGFA: Vascular Endothelial Growth Factor A WHO: World Health Organization XIAP: X-linked Inhibitor of Apoptosis Protein References Bolton JL, Trush MA, Penning TM et al (2000) Role of quinones in toxicology
Antioxidant/Vitamin Supplemental Therapy Excessive reactive nitrogen species and ROS can be formed when there is brain injury
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The preparation of this article benefited from countless discussions within our laboratory and collaborative network, which provided both intellectual stimulation and critical perspectives
Li X, Cai J, Zhang H, Sun S, Zhao S, Wang Z, Nie X, Xu C, Zhang Y, Xiao H
