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For general laboratory handling, refrigeration is commonly considered the standard approach after reconstitution

Hydrochloric acid is also necessary for the stomach to produce intrinsic factor, so there is less hydrochloric acid

A lyophilized product will have a different weight compared to its original state, meaning that care must be taken when measuring out the right amount of bacteriostatic water for reconstitution

Our gastroenterology specialists at Cleveland Clinic can help.

In addition to dietary intake, malabsorption conditions like celiac disease, atrophic gastritis, and inflammatory bowel diseases, all of autoimmune nature and frequently associated with autoimmune thyroid diseases, must be taken into account when vitamin B12 requirements are evaluated [97,98,99]