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When NNMT activity is dialed down, it allows for increased levels of nicotinamide adenine dinucleotide (NAD+), a coenzyme absolutely critical for countless metabolic processes, including energy production and cellular repair

For a 100kg person, that translates to approximately 22.5kg (49.5 pounds) over 18 months

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The deltoid, thigh and upper outer buttock each have different amounts of tissue over the muscle

When they are depleted, even simple daily tasks can feel exhausting