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Similarly, luteolin upregulates E-cadherin and downregulates mesenchymal markers such as N-cadherin, and vimentin expression, thereby restoring the epithelial phenotype of TNBC cells (Jo et al., 2015)

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Abbreviations ACSL4: acyl-CoA synthetase long-chain family member 4 AMPK: AMP-activated protein kinase CISD1: CDGSH iron sulfur domain 1 CP: ceruloplasmin DSF: disulfiram GPX4: glutathione peroxidase 4 GSH: glutathione HCC: hepatocellular carcinoma HIF1: hypoxia-inducible factor-1 ICIs: immune checkpoint inhibitors lncRNAs: long noncoding RNAs METTL14: methyltransferase-like 14 MT-1G: metallothionein-1G ncRNAs: noncoding RNAs NRF2: nuclear factor E2-related factor 2 RCD: regulated cell death ROS: reactive oxygen species SCD1: stearoyl-coenzyme A desaturase-1 SLC7A11: solute carrier family 7 member 11 SREBP1: sterol regulatory element-binding protein 1 S1R: Sigma 1 receptor TAZ: transcriptional coactivator with PDZ-binding motif TEAD: transcriptional enhanced associate domain YAP: Yes-associated protein Declarations Funding Hong Kong Scholars Program (Grant No

The positive effect of black seed (Nigella sativa L.) essential oil on thyroid hormones in rats with hypothyroidism and hyperthyroidism

21 great-grandchildren and several great-great-grandchildren