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These cytokines promote osteoclastogenesis and precipitate bone loss (179)

However, targeting of IFN / IFNGR1 can directly have pleotropic effects 29 , as indicated by our finding that IFNGR1 knockout tumors were significantly larger than IFNGR1 wild-type tumors in mice treated with IgG control

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Gutscher M, Pauleau AL, Marty L, Brach T, Wabnitz GH, et al

500 L of cell lipid extract) was cleaned up by solid-phase extraction (SPE) using a 100 mg Silica-Si SPE cartridge (Strata SI-1 Silica, Phenomenex, UK)