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Zheng M, Jiang Q, You J, Gao B, Cui W, Yao W, et al

A Phase II clinical trial involving 180 pregnant women suggests that metformin (3 g daily dose) can extend the gestational weeks of early-onset preeclampsia by about 1 week and reduce neonatal hospital stay (108)

For Mb@Gd-NTs + RT, the tumor sites were irradiated with a dose of 2 Gy on days 0, 2, 4, 6, 8, and 10 for a total dose of 12 Gy, and Mb@Gd-NTs were intravenously injected with a dose of 27.15 mg/kg (20 mol/kg) 24 h before each RT session

Such a catalyst was constructed via the coordination of a manganese porphyrin MnTCPP + and Zn 2+ , between which the MnTCPP + provides an active Mn III site with a coordination environment analogous to those of the active metal sites of Mn-SOD and catalase, while Zn 2+ upregulates the redox potential of the coordinated MnTCPP + , making the 2D MOF present considerable SOD- and catalase-like activities

Therefore, given that the solubility of LS-102 has been markedly improved compared to the precursor compound AS-IV, it can be employed as a novel synthetic drug containing carboxylic acid to treat metabolic diseases such as obesity through oral administration (21,215)

J Neuroinflamm (2020) 17(1):11