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Only a trial by Lapatto et al

Unlike synthetic B12 forms, methylcobalamin is ready for the body to use immediately and does not require conversion

Current approaches include: Continuous Use Approach: Based on clinical trials that used continuous daily administration for 12-24 weeks without scheduled breaks

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This trend not only reduces administrative burden but also improves claim accuracy, accelerates reimbursement, and minimizes the risk of denials or audits