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DOI: 10.1038/s41598-019-43013-z 40

Diabetic gastroparesis

Studies suggest the prevalence of deficiency in the UK is one in 10 people aged 75 and over, one in 20 aged 65-74, and lower in younger age groups except for vegans, where prevalence is around 11%

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Low vitamin B12 levels are not uncommon in vegan women who do not supplement adequately, and it is likely that infants breastfeed by women with low B12 levels can have low levels themselves

The mechanisms underlying this age-related NAD+ depletion involve multiple factors, including increased consumption by DNA repair enzymes, reduced biosynthesis, and enhanced degradation by CD38 and other NAD+-consuming enzymes