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doi: 10.21037/tau.2019.12.45

Melphalan Penetration of the Blood-Brain Barrier Via the Neutral Amino Acid Transporter in Tumor-Bearing Brain

The interaction between drugs and different types of proteins (in vivo) can alter the molecular characteristics of drugs and ultimately activate them

Karey KP and Sirbasku DA

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5.0 Pharmacological properties 5.1 Mechanism of Action/ Pharmacodynamic properties Glutathione is an extremely important cell protectant which directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules