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Ribose 5-phosphate is a pentose phosphate, consisting of the 5-carbon sugar, ribose, an essential component for nucleotides and nucleic acids

Nanocarrier-based strategies to enhance targeted modulation of signaling pathways in ischemic AKI (Table 2) Despite the robust renoprotective effects of natural compounds in experimental models of ischemic acute kidney injury (AKI), their clinical translation has been hampered by unfavorable pharmacokinetic properties, including poor aqueous solubility, rapid systemic metabolism, limited oral bioavailability, and insufficient accumulation within injured renal tissue

A non-targeting siRNA duplex was used as negative control

Abstract Metabolic syndrome (Mets) is an important contributor to morbidity and mortality in cardiovascular, liver, neurological, and reproductive diseases

Gu J, Zhang L, Swisher SG , Liu J, Roth JA, Fang B

Detailed analyses, including the forest plot, scatter plot, and leave-one-out analysis, are presented in Figure S3