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The quality of included studies assessed with the Newcastle-Ottawa scale is available in supplemental Table 2

The exposure of colorectal cancer cell lines to sublethal doses of paclitaxel fostered an epithelial-to-mesenchymal transition, which was antagonized by all-trans retinoic acid (ATRA) co-treatment

doi: 10.1007/s11064-018-2530-y, 40

Human sorbitol dehydrogenase gene

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The concentration of AF used to achieve this affect was well tolerated by the mice in this and previous studies [46], and it was reported previously that mammalian cells have over 95% viability when cultured in 10 M AF [68]