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10.1164/arrd.1979.120.4.893 41 TuY

PloS One 7 , e46037 (2012)

Because ssDNA is prone to adopt secondary structures at low forces, we conclude that RPA-Mer3 interaction is required for efficient Mer3-mediated unwinding, possibly through a combination of allosteric regulation of the helicase, and by preventing DNA structures from forming proximal to the helicase