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J Bioenerg Biomembr , 36:329333

29 (1 Part 2): 242247

M.van de SteegE.van BilsenJ.MeijerinkM

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Conversely, elevation of GPx4 can weaken the activation of the nuclear factor B pathway, thus alleviating renal fibrosis (223)

For this, however, NAM is used at millimolar concentrations, which are rarely attained under physiological conditions, as NAMPT and NNMT activities prevent NAM accumulation