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Increased awareness campaigns and school-level screening programs driving earlier diagnosis of pediatric growth disorders globally

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Gene replacement therapies are under investigation, including LX2006 by Lexeo Therapeutics in collaboration with Weill Cornell, which is in a Phase 1/2 trial (NCT05445323)

Tesamorelin: a growth hormone-releasing factor analogue for HIV-associated lipodystrophy

DSIP's action involves: Modulation of Neurotransmitters: DSIP may affect levels of serotonin and norepinephrine, which are involved in mood and relaxation

This approach seeks to address issues related to multiple comparisons, statistical power, population stratification, and failure to replicate from which previous population-based or casecontrol pharmacogenetic association studies may suffer