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(2005) Cobalamin dose regimen for maximum homocysteine reduction in end-stage renal disease

that is, data points for PBS-treated Tbx1 +/ and WT animals cluster together, as they do for vB12-treated Tbx1 +/ and WT animals, but the respective clusters are distant from each other (Fig S4A)

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Why frequency is individualized Because response depends on individual metabolism, the underlying reason for use, and adherence, the cadence of injections is a clinical decision