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enhancing mitochondrial energy metabolism and improving impaired cerebral basal metabolism may be a more effective treatment approach

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In subsequent studies, it was reported that GPx-1 could also protect against cell death in response to cytotoxic drugs, such as doxorubicin, and in response to direct ligand-mediated apoptosis, by ligand for CD95 receptor (CD95L) (142, 143)

Possible pathogenic variants include autosomal dominant (SNCA, and LRRK2) and autosomal recessive (Parkin, PINK1, and DJ-1) mutations

These findings suggested that the uptake pathway of NMN could be via a cell- or tissue-specific manner