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It happens because the body cannot make enough healthy red blood cells to carry oxygen to your tissues, so your cells struggle to function efficiently

However, some observational studies have linked very high supplemental intakes of B12 with potential health risks, including increased rates of certain cancers or fractures in specific populations

doi: 10.21037/tau.2019.11.30

sparse but functional cardiac GCGR engagement drives the dose-scaling excess (36 bpm) unique to this class

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Moderna's submission is based on two 25-microgram doses given 28 days apart