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Kawaguchi Y, Kopetz S , Tran Cao HS, Panettieri E, De Bellis M, Nishioka Y, Hwang H, Wang X, Tzeng CD, Chun YS, Aloia TA, Hasegawa K, Guglielmi A, Giuliante F, Vauthey JN

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They can't reproduce any faster than the prey population is reproducing

Moreover, hDPCs are prone to proliferative senescence and functional decline during serial passaging, further constraining scalability and reproducibility for large-scale manufacturing [14,15,16]

1 Introduction Pulmonary fibrosis (PF) is a progressive lung disease characterized by high mortality, abnormal proliferation of lung fibroblasts, inflammatory damage, tissue destruction, and scarring (Thannickal et al., 2004)