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[DOI] [PMC free article] [PubMed] [Google Scholar] Sommer B, Keinanen K, Verdoorn TA, Wisden W, Burnashev N, Herb A, Kohler M, Takagi T, Sakmann B, Seeburg PH

cat# A006) was intraperitoneally administered to female mice

Building upon the understanding of quercetins physicochemical properties, pharmacokinetics, bioavailability toxicological studies and safety, it is crucial to explore its potential therapeutic applications

Access this article Similar content being viewed by others Abbreviations AITC: Allyl ITC BITC: Benzyl ITC CDK: Cyclin-dependent kinase Cox-2: Cyclooxygenase 2 CYP: Cytochrome P450 ESP: Epithiospecifier GSH: Glutathione GST: Glutathione S-transferase HO-1: Heme oxygenase 1 iNOS: Inducible nitric oxide synthase ITC: Isothiocyanate Keap1: Kelch-like ECH-associated protein 1 MRP: Multidrug resistance associated protein NAC: N -acetylcysteine NQO1: NAD(P)H:Quinone Oxidoreductase Nrf2: Nuclear factor erythroid-derived 2-like 2 PEITC: Phenylethyl ITC ROS: Reactive oxygen species SF: Sulforaphane TR1: Thioredoxin reductase 1 References Ambrosone CB, McCann SE, Freudenheim JL et al (2004) Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype