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Description

If possible, every 1-2 miles on a long ride, make a fist and squeeze the hand 10-15 times

Area of application: Vitamin B12 deficiency that cannot be remedied nutritionally

[PMC free article: PMC2439524] [PubMed: 18500378] 47

Among different cell types, red blood cells (RBCs) have a strong dependence on G6PDH due to their lack of mitochondria, making G6PDH an essential NADPH source for preventing RBCs against oxidative damage caused by reactive oxygen species (ROS) (Prankerd, 1961

These ROS oxidize PUFAs in cell membranes into lipid peroxides (PUFA-OOH), thereby destroying cell membrane structural stability, attacking cellular DNA and proteins, and causing ferroptosis

If freezing is necessary, aliquot the reconstituted peptide into single-use volumes immediately after mixing, freeze once, and thaw only the amount needed for immediate use