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This restoration of GABAergic signaling helped in reducing glutamate excitotoxicity, nevertheless the improvements were modest compared to the effects observed with combination therapy

Vitamin D plays a very prominent role in immune responses and low vitamin D status is often described in the context of autoimmune and inflammatory diseases

While prolonged and repeated use of doxycycline is not recommended while breastfeeding, it's generally considered safe for short-term use

In preclinical studies, the compound is being examined for its growth factor signaling, cellular proliferation, and metabolic pathway regulation