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It ameliorated injury in isolated perfused rat heart (Tanguy et al., 2006) and increased the lifespan and neuroprotective action in a Philodina acuticornis (a species of freshwater bdelloid rotifers) model (Poeggeler et al., 2005)

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Cortisol or corticosterone concentrations remain near baseline in controlled models, thereby reducing glucocorticoid-driven counterregulatory effects that may otherwise complicate analysis of musculoskeletal recovery