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Journal of biological chemistry [J], 2001, 276 (16): 12749-12755

doi: 10.1371/journal.pone.0025340 44 BruceMRCouchACMGrantSMcLellanJKuKChangCet al

Moreover, the mammalian target of rapamycin (mTOR) complex family proteins regulates ferroptosis by manipulating SLC7A11 (Xu et al., 2021)

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When Hedgehog binds to PTCH, activated Smo transmits signals through Gli, Sufu, and Kif7, resulting in the generation of the Gli-activated form (GliA), which translocates to the nucleus and leads to transcriptional activation of Hh target genes