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The concept of selective insulin resistance is therefore critical for understanding the complex pathophysiology of T2DM, in which the insulin resistant state prevails in many tissues, but in a tissue-dependent, pathway-specific manner

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These sources include the following: Fish and shellfish Liver Red meat Eggs Poultry Dairy products such as milk, cheese, or yogurt Fortified nutritional yeast Fortified breakfast cereals Enriched soy or rice milk However, our bodys ability to absorb vitamin B12 diminishes as we age

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Both unborn and newborn babies have a special need for vitamin B12 and if the mother is a vegetarian or a vegan, this need may not be met either through her diet for the unborn or through her breast milk for the newborn

Common signs include: Persistent fatigue or weakness Pale or slightly yellow skin Shortness of breath Tingling or numbness in the hands and feet Difficulty with memory or concentration In more advanced cases, neurological symptoms may become more pronounced