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Even though endometriosis lesions can be surgically removed, the recurrence rate is high, with a 2-year recurrence rate of 21.5% and a 5-year recurrence rate of 40% - 50%

Channels created by microneedling begin closing within minutes

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238 Due to the high energy requirements, both cardiac and skeletal muscles are rich in mitochondria but also influenced by oxidant stress and high rates of fuel oxidation

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Furthermore, elevated levels of inflammatory and oxidative stress markers, such as TGF- and VEGF, suggesting that inflammation plays a critical role in disease progression (319, 320)