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10.1016/0165-1781(79)90006-4 34 DecressacM.MattssonB.WeikopP.LundbladM.JakobssonJ.BjrklundA

doi:10.1016/0006-2952(91)90363-A

Glutamine affects T24 bladder cancer cell proliferation by activating STAT3 through ROS and glutaminolysis

In addition, ectopic expression of Sirt5 compensates for the reduction of ATF4 due to glutamine deprivation-induced stress in stressed cells [230]

Its antioxidant properties allow it to eliminate harmful substances like free radicals from the body, which help protect the individual from the accumulation of oxidative stresses and diseases

Tumor-secreted protease cathepsin C (CTSC) activates neutrophil membrane-bound proteinase 3 (PR3), leading to the promotion of IL-1 processing and NF-B activation, thereby enhancing the secretion of IL-6 and CCL3 for neutrophil recruitment