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On the other hand, high-dose vitamin C has shown to be pro-oxidant, selectively killing cancer and other G6PD deficient cells.It also has some anti-inflammatory activity resulting in suppression of tumor proliferation, angiogenesis, and metastasis

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This modification is catalyzed by CBP/p300 and has functional effects, since it attenuates p53 acetylation and downregulates the transcriptional activity of target genes including Cdkn1a (p21) Puma , which are involved in cell cycle arrest and apoptosis, respectively (Liu et al., 2019b)

The present results suggest that Nano-Brb enhanced the lungs architecture and functional performance by modulating inflammatory cytokines, oxidative stress, gene expression, and histopathological damage

The difference in study results could be due to diet