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E., & Cravatt, B

doi: 10.2337/dc11-2055 183 DeleskogALjungRForsellYNevrianaAAlmasAMllerJ

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Herein we report on characterization of the acyl group- and site-selectivity of seven human sirtuins using acylated nucleosomes as substrates, by quantitative mass spectrometry-based analysis

Most others who Ive spoken with that had more severe acute reactions like nausea etc

One of the principal aims of this study was to develop a working example of synthetic prodrugs that can be activated in vivo using artificial metalloenzymes