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Though created for veterinary use in rats and racehorses, TB500 has gained attention as a potential therapeutic peptide

Shaking the vial creates mechanical stress that can break the delicate bonds holding the amino acid chains together, a process called denaturation

However, many of these models were established using small animals, such as mice, rats and rabbits, which involve different characteristics from the human spine, particularly in terms of disc anatomy and mechanical loading of vertebrae

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Mark the reconstitution date on the vial

Biochemistry 45 (51): 1518815196