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We have recently reported indirect evidence for this model

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This cross-reactivity means metabolic effects (including hypoglycemia at higher doses) are possible in research models and should be monitored in in vivo protocols

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L-carnitine side effects are generally mild but may include: Nausea, vomiting, or abdominal cramps Diarrhoea or heartburn A 'fishy' body odour (due to trimethylamine production by gut bacteria) Rarely, restlessness or sleep disturbances High doses of L-carnitine (above 3g daily) have been associated with increased seizure frequency in individuals with seizure disorders

Recent work in mice has shown that CD40 activation triggers FAO, which supports histone acetylation and subsequent epigenetic reprogramming of pro-inflammatory genes and anti-tumorigenic phenotypes