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A placebo-controlled trial in 252 patients with major depressive disorder who were randomized to 12-weeks NAC or placebo added to standard antidepressant treatment, and followed up to 16 weeks, found no significant differences in depressive symptoms assessed using the Montgomery-sberg Depression Rating Scale (MADRS) between the two groups at week 12 (primary endpoint) [144]

Skin wound studies show accelerated closure, reduced scarring, and improved structural integrity of healed tissue

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Its true that vitamin C has an important function in the body, but its controversial whether taking additional vitamin C orally or by injection offers any advantage for people who consume adequate vitamin C in their diet

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A 2024 pilot study in interstitial cystitis represents one of few published human-cohort efforts (PMID 39325560), though it is small and single-centre