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PMID: 31526696

Coronary heart disease (CHD) is a globally prevalent cardiovascular disorder with a complex pathogenesis associated with multiple risk factors, including high-level low-density lipoprotein cholesterol, smoking, chronic kidney disease, diabetes and hypertension (1)

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Pomiferin, especially at 300 mg/kg, preserved mitochondrial integrity and exerted anti-apoptotic effects

Revascularization is an effective strategy for salvaging ischemic myocardium in myocardial infarction [194, 195], while restoration of blood flow to the ischemic myocardium paradoxically exacerbates cardiac tissue damage, a phenomenon known as myocardial ischemiareperfusion (I/R) injury [196, 197]

It has been proposed that mitochondrial dysfunction and oxidative stress contribute to the incidence and progression of neurological disorders involving Alzheimers disease