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At the titrated once-daily doses, roughly one vial covers a 34 week phase at these once-daily doses, so plan several vials for a full course

Moreover, genome-wide association studies (GWAS) across different ethnic groups have identified polymorphisms in over 70 non-HLA loci, some of which include key protein-encoding genes that have been shown to play an immune-associated function ( Figure 1 ) (56, 67, 68)

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The public docket (FDA-2025-N-6895) is open for written comments at regulations.gov

Even over-the-counter medications like acetaminophen (Tylenol) can cause serious liver damage when combined with alcohol