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Theoretical concerns: Because DSIP interacts with the opioid system and ACTH axis in animal models, chronic use could theoretically affect neuroendocrine regulation

Devices 19 , 273280 (2022)

Zonula occludens toxin (Zot, or zonulin), an enterotoxin secreted by intestinal epithelial cells following stimuli from diets or microbiota, was shown to be a potent regulator of TJ competency and intestinal barrier function

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This peptide influences immune cells, regulates apoptotic cells, and helps restore DNA patterns that normally get corrupted in cancer patients

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