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One effect of ageing is reduced energy production and impairment of cells

Superoxide dismutases (SOD) three forms exist, SOD1 (Intracellular), SOD2/MnSOD (Mitochondrial), SOD3 (Extracellular) Catalase (CAT) Glutathione peroxidase (GPx) In addition to these enzymes, glutathione transferase, ceruloplasmin, hemoxygenase and possibly several other enzymes may participate in enzymatic control of oxygen radicals and their products

Letavernier E, Vandermeersch S, Traxer O, Tligui M, Baud L, Ronco P et al (2015) Demographics and characterization of 10,282 Randall plaque-related kidney stones: a new epidemic