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Patients with diabetes are already at risk of neuropathy, and low B12 means worse neuropathy

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176 This finding demonstrated that the Wnt/-catenin pathway restores tissue integrity after acute liver injury

Typical doses range from 250-1000 mg daily, though clinical evidence supports only modest benefits at lower doses

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At the same time, in our previous study on the protective effect of Ebselen on renal ischemia-reperfusion injury, we found that the expression level of GPX3 in renal tissues decreased after renal IRI, and when the level of GPX3 increased after the use of Ebselen, the pathological damage of renal histologic damage was alleviated, and we speculated that GPX3 may play an important role in the oxidative stress response of renal ischemia-reperfusion injury (Wu et al., 2022)