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OH Py 2 N 2 treatment dose-dependently decreased the production of ROS (Figures 3C,D)

In analyses of ChIP-seq data, we observed that many of these genes were devoid of NRF2 in their promoter regions

Brioukhanov, A.L., Nesatyy, V.J., and Netrusov, A.I., Biochemistry (Moscow), 2006, vol

5a,b and Extended Data Fig

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These compounds were also shown to block the activity of 5-reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT), which promotes prostate growth (Evans 1995)