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Description

1) used nontryptic (peptidomic) liquid chromatography mass spectrometry (LCMS) on 102 post-mortem cortical samples derived from individuals in four distinct diagnostic classes: control (low neuropathology, retained cognition), AD-resilient (high neuropathology, retained cognition), frail (low neuropathology, impaired cognition) and AD-dementia (high neuropathology, impaired cognition)