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Parietal cells in the stomach produce a glycoprotein called intrinsic factor, which is necessary to absorb vitamin B12 in the terminal ileum

They bypass the gut entirely, which is crucial if absorption is impaired

Vitamin B12 has many functions in the body: among other things, it contributes to normal energy metabolism, to the reduction of tiredness and fatigue and to the normal formation of red blood cells

Intrinsic factor antibodies are much less sensitive than parietal cell antibodies, but they are much more specific

According to a case report published in June of 2018 in the Journal of Orthomolecular Medicine , intravenous therapies were shown to help treat acute viral infections

Vitamin B12 deficiency common in primary hypothyroidism