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Endpoint measurements may include 14 CO 2 capture for complete oxidation, 14 C-labeled acid-soluble metabolites for partial oxidation products, isotope tracing of labeled carbon into downstream intermediates, oxygen consumption, or acylcarnitine profiling by tandem mass spectrometry

14 However, the mechanism of vision loss in OPGs is still unclear

Jeon G, Kim Y, Choi SY et al (2021) Melanin decolorization by lysosome-related extract in Saccharomyces cerevisiae modified to overproduce glutathione peroxidase

Figure 1: Changes in body weight from baseline to the end of treatment at week 26 associated with the trial product estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo

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