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GHK affect the gene expression of almost 32.1% of human genes

Journal of Biomaterials Science, Polymer Edition, 19(8), 969-988.Review of GHK and GHK-Cu in tissue remodeling and extracellular matrix research from a perspective in the originating research community

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Goldstein AL, Hannappel E, Kleinman HK

However, avoid using them with highly acidic products, such as strong AHAs or retinoids, which may interfere with their effectiveness

The experimental setup involved exposure of dermal fibroblasts with various combinations of GHK-Cu and HA, measuring the synthesis of collagen types I, IV, and VII