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Oxidative stress and viral infections: rationale, experiences, and perspectives on N-acetylcysteine

The rationale behind these sensors is the ability of a metabolite to induce a conformational change in a specific protein that is fused to a circular permuted fluorescent protein (cpFP)

Mena NP, Urrutia PJ, Lourido F, Carrasco CM, Nez MT

We also found that treating mice with a methionine-restricted cysteine-depleted diet is safe and decreased glutathione levels in vivo

Chair - Multimodality of Advanced Lung Cancer Track

Remarkably, ~5090% reduction of L68Q-hCC staining was observed in five of the treated carriers suggesting that L68Q-hCC is a clinical target for reducing agents