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However, clinically meaningful weight loss usually occurs between 8 and 12 weeks of treatment

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In certain embodiments, the dose is between 0.001 mg/kg patient weight to about 15 mg/kg per kg patient weight per administration, or 0.01 mg/kg to about 1.5 mg/kg

This preservative keeps the solution sterile and safe for extended use from a multi-dose vial, provided aseptic technique is followed

In a recent report, MM cells from patients who discontinued treatment with daratumumab, due to disease progression, appeared to retain cell-surface expression of CD38 [33]