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3 , e1700344 (2017)

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Un polipptido modificado que presenta resistencia aumentada a un inhibidor presenta, por ejemplo, un aumento del 1 %, 2 %, 3 %, 4 %, 5 %, 6 %, 7 %, 8 %, 9 %, 10 %, 20 %, 30 %, 40 %, 50 %, 60 %, 70 %, 80 %, 90 %, 91 %, 92 %, 93 %, 94 %, 95 %, 96 %, 97 %, 98 %, 99 %, 100 %, 200 %, 300 %, 400 %, 500 %, o ms resistencia a los efectos de un inhibidor en comparacin con un polipptido sin modificar

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ORM1 is linked to inflammatory responses, lipid localization, and foam cell differentiation, while MANBA contributes to extrinsic apoptotic signaling and regulates lipid metabolism and plasma lipoprotein levels