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& Tang, R

10.1016/j.medmal.2013.10.002 22 CannarellaL

doi:10.31083/j.rcm2305181

Despite the high risk and costs associated with clinical trials, the pharmaceutical industry is pursuing the development of neuroprotective drugs due to the major health and economic burden that stroke has on the aging population

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However, extreme oxidation breaks the balance between the oxidative and antioxidant systems, resulting in oxidative stress and an excessive accumulation of ROS