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Together, these findings demonstrate that, in contrast with acute exposure, chronic disruption of iron homeostasis with consequent GSH depletion remodels cellular redox homeostasis over time, inducing a state we term chronoferroptosis: a persistent ferroptotic adaptation characterized by coordinated alterations in iron-handling and antioxidant defense proteins that may represent early vulnerability to neurodegenerative pathology

10.1104/pp.112.199703 Plant Physiol

Think of glutathione as your internal guardian, protecting your cells from harm and ensuring your body operates at its best

mBio 11 , e03313-19 (2020)

As aging progresses, the accumulation of lipid peroxides increases, causing instability in cell membranes, particularly in muscle cells

Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders