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Aggrecan and COL2 immunostaining were used to assess cartilage formation within the graft

In our case, treatment was initiated with methylene blue, with the maximum cumulative dose administered within the first 24 h

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In apoptosis, -sitosterol upregulates pro-apoptotic factors such as p53 and Bax, while downregulating anti-apoptotic proteins such as Bcl-2, leading to an increase in mitochondrial outer membrane permeability and the activation of key apoptotic enzyme cascades such as caspase-9 and 3, which induces programmed cell death (83)

Together, DNMT1 overexpression and the resulting gene silencing contribute to GABAergic dysfunction and neural circuit disruptions in schizophrenia

mean and p values indicated, unpaired (two-sided) t-test