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Disruptions in iron metabolism, lipid metabolism, and the collapse of cellular oxidative defense systems can accelerate the production of lipid peroxides, damaging the CNS and leading to secondary injuries in acute CNS injuries and NDDs (Ratan, 2020)

J Biol Chem 244:60496055 Meir JU, Champagne CD, Costa DP et al (2009) Extreme hypoxemic tolerance and blood oxygen depletion in diving elephant seals

To balance the antibacterial activity and cytotoxicity, we selected a concentration of SeC@PA containing 20 g/mL of Se, 7.2 g/mL of Ce6, and 10.8 g/mL of LA for follow-up studies

The triple drug regimen of FLT3 inhibitor, glycolysis inhibitor (2-DG), and anti-PD-L1 antibody can synchronously block the energy supply and the immune checkpoint pathway through the metabolic-immune dual-targeting mechanism (129)

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Therefore, a comprehensive analysis of the eukaryotic groups should be performed in future studies